Nutrition scientists at our lab are collaborating on research exploring dietary patterns modeled after non-industrialized eating habits. Early human trials show that diets high in fiber and minimally processed foods can improve metabolic and immune markers within weeks. Participants following this dietary pattern demonstrated reduced cholesterol, lower blood glucose, and decreased inflammatory biomarkers, alongside measurable […]
Our cellular metabolism division is examining a newly discovered regulatory mechanism involving hormone-sensitive lipase (HSL), a protein historically known only for breaking down fat. New evidence shows HSL also functions within the nucleus of fat cells, helping regulate adipocyte development and stability. When HSL function is impaired, fat tissue can shrink abnormally, leading to metabolic […]
Scientists in our metabolic physiology unit have contributed to new findings showing that methane-producing microbes may determine how efficiently people extract calories from high-fiber foods. The research suggests that methanogenic microbes help stabilize gut fermentation processes, allowing more energy to be generated from otherwise indigestible carbohydrates. Participants with higher methane production also showed increased short-chain […]
A new study from our metabolism and nutrition research team has revealed that the gut microbiome may act as a key biological bridge between diet quality and metabolic disease risk. By analyzing hundreds of adults across a wide metabolic spectrum, researchers identified microbial signatures that influence how nutrients are processed, stored, and converted into energy. […]